On-premise medical AI agents for reliable clinical decision-making
Zhang L, Wölflein G, Ferber D, …, Kather JN.
Science
Publications
Selected work co-authored by IMAI investigators and the complete publication archive of the institute’s founding director
This archive includes earlier work by IMAI’s founding team at TU Dresden, Heidelberg University Hospital, and collaborating institutions.
Highlights
Selected research
Towards autonomous medical artificial intelligence agents
Ferber D, Hilgers L, Höper C, Kinny-Köster B, Eckardt JN, Egger-Heidrich K, …, Jäger D, Kather JN.
Safety and security of large language models in healthcare
Clusmann J, Freyer O, Ostermann M, Ferber D, Ghaffari Laleh N, Hilgers L, …, Wiest IC, Kather JN.
Large language models as experimental systems in human psychopathology: a modelling study
Wekenborg MK, Michels EAM, Kurze G, Kropp ML, Wolf F, Harzbecker J, Wiest IC, Kather JN.
ESMO Basic Requirements for AI-based Biomarkers In Oncology (EBAI)
Aldea M, Salto-Tellez M, Marra A, Umeton R, Stenzinger A, Koopman M, …, Westphalen CB, Kather JN.
ESMO guidance on the use of Large Language Models in Clinical Practice (ELCAP)
Wong EYT, Verlingue L, Aldea M, Franzoi MA, Umeton R, Halabi S, …, Koopman M, Kather JN.
Development and validation of an autonomous artificial intelligence agent for clinical decision-making in oncology
Ferber D, El Nahhas OSM, Wölflein G, Wiest IC, Clusmann J, Leßmann ME, …, Truhn D, Kather JN.
Multimodal histopathologic models stratify hormone receptor-positive early breast cancer
Boehm KM, El Nahhas OSM, Marra A, Waters M, Jee J, Braunstein L, …, Shah SP, Kather JN.
From whole-slide image to biomarker prediction: end-to-end weakly supervised deep learning in computational pathology
El Nahhas OSM, van Treeck M, Wölflein G, Unger M, Ligero M, Lenz T, …, Truhn D, Kather JN.
Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study
Wagner SJ, Reisenbüchler D, West NP, …, Boxberg M, Peng T, Kather JN.
Swarm learning for decentralized artificial intelligence in cancer histopathology
Saldanha OL, Quirke P, West NP, …, Hoffmeister M, Truhn D, Kather JN.
Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer
Kather JN, Pearson AT, Halama N, …, Hoffmeister M, Trautwein C, Luedde T.
Bibliography
Complete publication archive
Search by title, author, journal, year or research area.
337 publications
2026
Large Language Models for Oncology Guideline Maintenance: Prospective Case Study
JMIR AI
2026
Safety and security of large language models in healthcare
Nature
2026
Survival of Colon Cancer in a Population-Based Cohort Study: A Comprehensive Analysis of Location of the Primary Tumor
Cancer Medicine
2026
Machine learning for population-level risk prediction of future cholangiocarcinoma
EBioMedicine
2026
Leave No Data Behind: Exploring a new paradigm in oncology with foundation models and large language models
Cell Reports Medicine
2026
Prompt injection attacks on vision-language models for surgical decision support
npj Digital Surgery
2026
Developing a Histology-Based Artificial Intelligence Biomarker to Predict Adjuvant Chemotherapy Benefit in Pancreatic Cancer
Journal of Clinical Oncology
2026
The rise of AI-generated presentations at scientific meetings
JHEP Reports
2026
The Cost of Accessibility: Considerations for Adopting Microscope Camera-Derived Images for Digital and Computational Pathology
Mayo Clinic Proceedings Digital Health
2026
CLEAR: an auditable foundation model for radiology grounded in clinical concepts
Nature Biomedical Engineering
2026
Clinician expertise and prompt engineering enhance cancer information extraction in electronic health records by small language models
Communications Medicine
2026
How to benchmark medical AI agents
PLoS Medicine
2026
Generalizable and explainable deep learning for brain MRI: a multi-cohort evaluation of 3D architectures for age and sex prediction
Brain Informatics
2026
AI-based selection of tumor regions for genomic profiling in neuropathology
Neuro-oncology Advances
2026
Established machine learning matches tabular foundation models in clinical predictions
BMC Medical Informatics and Decision Making
2026
Mutation enrichment in targeted panels flags immunotherapy-responsive POLE-driven hypermutated microsatellite-stable colorectal cancers
npj Precision Oncology
2026
A deep learning framework for efficient pathology image analysis
Nature Communications
2026
Clinical decision support in hematological malignancies using a case-grounded AI agent
Nature Medicine
2026
Erratum for: Associations of MRI-derived Paraspinal IMAT and LMM with Cardiometabolic Risk Factors: Results from a German Cohort
Radiology
2026
clickBrick prompt engineering: optimizing large language model performance in clinical psychiatry
npj Mental Health Research
2026
Functional Outcome Prediction in Young Adults With Mental Health Symptoms Using Machine Learning and Large Language Models: Longitudinal Observational Study
JMIR Mental Health
2026
Gut decisions based on the liver: prediction of colorectal neoplasia using AI-based liver analysis of routine CT scans
Frontiers in Oncology
2026
Towards autonomous medical artificial intelligence agents
Nature
2026
Counterfactual Diffusion Models Provide Interpretable Explanations of Artificial Intelligence Models in Pathology
Cancer Research
2026
Appendix300: Surgical video and patient metadata of 330 laparoscopic appendectomy cases from five institutions
Scientific Data
2026
SCRIPT: Stratified clinical risk prediction from pathology reports using large language models
Journal of Pathology Informatics
2026
Spatial biomarker discovery via interpretable semantic learning in histopathology
Cancer Cell
2026
Agentic AI for interdisciplinary clinical decision support in high-stakes care
JHEP Reports
2026
Large language models as experimental systems in human psychopathology: a modelling study
The Lancet Digital Health
2026
IBDome: An Integrated Molecular, Histopathological, and Clinical Atlas of Inflammatory Bowel Diseases
Gastroenterology
2026
Deep Learning Predicts Mutations and Outcomes in Gastrointestinal Stromal Tumors
Cancer Research
2026
Associations of MRI-derived Paraspinal IMAT and LMM with Cardiometabolic Risk Factors: Results from a German Cohort
Radiology
2026
Analysis of B-Scan Ultrasonography Using Neural Networks to Predict Risk of Fibrosis in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Ultrasound in Medicine & Biology
2026
A comprehensive bedside chest radiography dataset with structured, itemized and graded radiologic reports
Scientific Data
2026
HISTAI: a valuable dataset with a valuable lesson
The Journal of Pathology Clinical Research
2026
Machine Learning Predicts Hepatocellular Carcinoma Risk from Routine Clinical Data: A Large Population-Based Multicentric Study
Cancer Discovery
2026
Large language models in healthcare
Nature Reviews Nephrology
2026
Blocking the Reflection: Milestones and Hurdles for Digital Twins in Mental Health
Pharmacopsychiatry
2026
A clinical environment simulator for dynamic AI evaluation
Nature Medicine
2026
BCLC classification and AI-based image quantification: What is meant to be will come together - but how and when?
Journal of Hepatology
2026
Reporting checklist for foundation and large language models in medical research (REFINE): an international consensus guideline
Diagnostic and Interventional Radiology
2026
What practicing pathologists and oncologists should know about the new computational pathology-based companion diagnostic tools
The Journal of Pathology
2026
Artificial intelligence-generated synthetic data for cancer research and clinical trials
Nature Reviews Cancer
2026
Hallucination filtering in radiology vision-language models using discrete semantic entropy
European Radiology
2026
MedicalPatchNet: a patch-based self-explainable AI architecture for chest X-ray classification
Scientific Reports
2026
Deep learning-based H&E-derived risk scores in colorectal cancer: associations with tumour morphology, biology, and predicted drug response
The Journal of Pathology
2026
Benchmarking large language model-based agent systems for clinical decision tasks
npj Digital Medicine
2026
SwarmMAP: swarm learning for decentralized cell type annotation in single cell sequencing data
npj Systems Biology and Applications
2026
Artificial intelligence in oncology: from tools to teammates
Annals of Oncology
2026
Detection of esophageal varices and prediction of hepatic decompensation in unresectable hepatocellular carcinoma using AI
Journal of Hepatology
2026
Reply to: "Optimizing clinical adoption of large language models in hepatology: Toward terminological precision, multilingual adaptability, and interpretive literacy"
Journal of Hepatology
2026
Guidelines for Reporting Studies on Large Language Models in Radiology: An International Delphi Expert Survey
Radiology
2026
Collaborative and Cooperative Hospital "In-House" Medical Device Development and Implementation in the AI Age: The European Responsible AI Development (EURAID) Framework Compatible With European Values
Journal of Medical Internet Research
2026
Integrating artificial intelligence (AI) into colorectal cancer reporting
The Journal of Pathology
2026
Artificial Intelligence for Diagnostic Pathology in Nephrology
Journal of the American Society of Nephrology
2026
Artificial intelligence agents in cancer research and oncology
Nature Reviews Cancer
2026
Reducing manual workload in CT and MRI annotation with the Segment Anything Model 2
BMC Medical Imaging
2026
Enhancing Patient Empowerment Through Artificial Intelligence in Liver Cancer
The American Journal of Gastroenterology
2025
H&E-based MSI/MMR testing with AI in colorectal cancer: a multi-centred blinded evaluation
npj Digital Medicine
2025
If a therapy bot walks like a duck and talks like a duck then it is a medically regulated duck
npj Digital Medicine
2025
Collaborative framework on responsible AI in LLM-driven CDSS for precision oncology leveraging real-world patient data
npj Precision Oncology
2025
Artificial intelligence predicts outcome-related molecular profiles and vascular invasion in hepatocellular carcinoma
JHEP Reports
2025
Multimodal analysis of whole slide images in colorectal cancer
npj Digital Medicine
2025
Combining Clinician Expertise with Prompt Engineering enhances Small Language Models Reliability for Cancer Entity Recognition in Electronic Health Records
medRxiv
2025
Education Research: Can Large Language Models Match MS Specialist Training?: A Comparative Study of AI and Student Responses to Support Neurology Education
Neurology Education
2025
Decentralized, privacy-preserving surgical video analysis with Swarm Learning
medRxiv
2025
Adaptive validation strategies for real-world clinical artificial intelligence
Nature Computational Science
2025
Application of artificial intelligence and digital tools in cancer pathology
The Lancet Digital Health
2025
Constitutional epimutations in LTBP4, a component of the TGF-β signaling, and in BRCA1, as potential drivers of early-onset colorectal cancer
Clinical Epigenetics
2025
Diagnosing Autoimmune Hepatitis: Histological Correlations and Emerging Technologies
Liver International
2025
Pathologist-like explainable AI for interpretable Gleason grading in prostate cancer
Nature Communications
2026
Benchmarking foundation models as feature extractors for weakly supervised computational pathology
Nature Biomedical Engineering
2025
A software pipeline for medical information extraction with large language models, open source and suitable for oncology
npj Precision Oncology
2025
Chat GPT-4 shows high agreement in MRI protocol selection compared to board-certified neuroradiologists
European Journal of Radiology
2025
Histopathological evaluation of abdominal aortic aneurysms with deep learning
Diagnostic Pathology
2025
Appendix300: A multi-institutional laparoscopic appendectomy video dataset for computational modeling tasks
medRxiv
2025
The barriers to uptake of artificial intelligence in hepatology and how to overcome them
Journal of Hepatology
2026
A role for non-selective beta-blockers in preventing liver decompensation in patients with hepatocellular carcinoma undergoing systemic therapy
Journal of Hepatology
2025
The Impact of Access to Clinical Guidelines on LLM-Based Treatment Recommendations for Chronic Hepatitis B
Liver International
2025
Limited impact of real-world evidence in medical oncology: How can AI turn the tide
European Journal of Cancer (Oxford, England
2025
Large language models for clinical decision support in gastroenterology and hepatology
Nature Reviews Gastroenterology & Hepatology
2025
Assessing genotype-phenotype correlations in colorectal cancer with deep learning: a multicentre cohort study
The Lancet Digital Health
2025
HIBRID: histology-based risk-stratification with deep learning and ctDNA in colorectal cancer
Nature Communications
2026
Unconditional latent diffusion models memorize patient imaging data
Nature Biomedical Engineering
2025
Prompt injection attacks on vision-language models for surgical decision support
medRxiv
2025
Building digital histology models of transcriptional tumor programs with generative deep learning for pathology-based precision medicine
Genome Medicine
2025
LongHealth: A Question Answering Benchmark with Long Clinical Documents
Journal of Healthcare Informatics Research
2025
Overcoming regulatory barriers to the implementation of AI agents in healthcare
Nature Medicine
2025
Deep Learning Predicts Survival Across Squamous Tumor Entities From Routine Pathology: Insights From Head and Neck, Esophagus, Lung, and Cervical Cancer
Modern Pathology
2025
Vision-language models for automated video analysis and documentation in laparoscopic surgery: a proof-of-concept study
International Journal of Surgery
2025
Deep learning can predict cardiovascular events from liver imaging
JHEP Reports
2025
How machine learning on real world clinical data improves adverse event recording for endoscopy
npj Digital Medicine
2025
Benchmarking vision-language models for diagnostics in emergency and critical care settings
npj Digital Medicine
2025
Large language models-enabled digital twins for precision medicine in rare gynecological tumors
npj Digital Medicine
2025
AML diagnostics in the 21st century: Use of AI
Seminars in Hematology
2025
Medical slice transformer for improved diagnosis and explainability on 3D medical images with DINOv2
Scientific Reports
2025
The case for homebrew AI in diagnostic pathology
The Journal of Pathology
2025
Deep Learning Discovers New Morphological Features while Predicting Genetic Alterations from Histopathology of Papillary Thyroid Carcinoma
Thyroid
2025
End-to-end prediction of clinical outcomes in head and neck squamous cell carcinoma with foundation model-based multiple instance learning
BMC Artificial Intelligence
2025
Erratum to 'Use of artificial intelligence for liver diseases: A survey from the EASL congress 2024' [JHEP Reports (2024) doi https://doi.org/10.1016/j.jhepr.2024.101209]
JHEP Reports
2025
RadioRAG: Online Retrieval-Augmented Generation for Radiology Question Answering
Radiology Artificial Intelligence
2025
Intermuscular adipose tissue and lean muscle mass assessed with MRI in people with chronic back pain in Germany: a retrospective observational study
The Lancet Regional Health Europe
2025
Development and validation of an autonomous artificial intelligence agent for clinical decision-making in oncology
Nature Cancer
2025
Deep Learning Reveals Liver MRI Features Associated With PNPLA3 I148M in Steatotic Liver Disease
Liver International
2025
Dermatologist-like explainable AI enhances melanoma diagnosis accuracy: eye-tracking study
Nature Communications
2025
Galar - a large multi-label video capsule endoscopy dataset
Scientific Data
2025
Deep learning predicts microsatellite instability status in colorectal carcinoma in an ethnically heterogeneous population in South Africa
Journal of Clinical Pathology
2025
IBDome: An integrated molecular, histopathological, and clinical atlas of inflammatory bowel diseases
Research Square
2025
Identification and external validation of tumor DNA methylation panel for the recurrence risk stratification of stage II colon cancer
Translational Oncology
2025
IBDome: An integrated molecular, histopathological, and clinical atlas of inflammatory bowel diseases
bioRxiv
2025
Celebrating 5 years of Cell Reports Medicine with authors: Past and future
Cell Reports Medicine
2025
Examining human-AI interaction in real-world healthcare beyond the laboratory
npj Digital Medicine
2025
Stroma and lymphocytes identified by deep learning are independent predictors for survival in pancreatic cancer
Scientific Reports
2025
Mapping the landscape of biliary tract cancer in Europe: challenges and controversies
The Lancet Regional Health Europe
2025
Weakly Supervised Deep Learning Can Analyze Focal Liver Lesions in Contrast-Enhanced Ultrasound
Digestion
2025
Multimodal histopathologic models stratify hormone receptor-positive early breast cancer
Nature Communications
2025
End-to-end prediction of clinical outcomes in head and neck squamous cell carcinoma with foundation model-based multiple instance learning
medRxiv
2025
Assessing Genotype-Phenotype Correlations with Deep Learning in Colorectal Cancer: A Multi-Centric Study
medRxiv
2025
Density and entropy of immune cells within the tumor microenvironment of primary tumors and matched brain metastases
Acta Neuropathologica Communications
2025
A decision point between transdifferentiation and programmed cell death priming controls KRAS-dependent pancreatic cancer development
Nature Communications
2024
The Performance of Artificial Intelligence on a National Medical Licensing Examination—The Answers of Large Language Models to Text Questions
Deutsches Arzteblatt International
2025
Sex and outcomes of patients with microsatellite instability-high and BRAF V600E mutated metastatic colorectal cancer receiving immune checkpoint inhibitors
Journal for Immunotherapy of Cancer
2025
Benchmarking Vision Capabilities of Large Language Models in Surgical Examination Questions
Journal of Surgical Education
2025
Swarm learning with weak supervision enables automatic breast cancer detection in magnetic resonance imaging
Communications Medicine
2025
Prompt injection attacks on vision language models in oncology
Nature Communications
2025
Breaking frontiers with multidisciplinary cancer research
Nature Cancer
2025
SwarmMAP: Swarm Learning for Decentralized Cell Type Annotation in Single Cell Sequencing Data
bioRxiv
2025
Current applications and challenges in large language models for patient care: a systematic review
Communications Medicine
2025
Authors' reply: Re: Koga et al. Retrieval-augmented generation versus document-grounded generation: a key distinction in large language models
The Journal of Pathology Clinical Research
2025
Deep Learning for Biomarker Discovery in Cancer Genomes
bioRxiv
2024
Deep learning helps discriminate between autoimmune hepatitis and primary biliary cholangitis
JHEP Reports
2025
Discordance, accuracy and reproducibility study of pathologists' diagnosis of melanoma and melanocytic tumors
Nature Communications
2025
Advances in the understanding and therapeutic manipulation of cancer immune responsiveness: a Society for Immunotherapy of Cancer (SITC) review
Journal for Immunotherapy of Cancer
2025
Artificial intelligence-based biomarkers for treatment decisions in oncology
Trends in Cancer
2025
The spatially informed mFISHseq assay resolves biomarker discordance and predicts treatment response in breast cancer
Nature Communications
2024
How AI agents will change cancer research and oncology
Nature Cancer
2025
Deep Learning-Based Detection of Malignant Bile Duct Stenosis in Fluoroscopy Images of Endoscopic Retrograde Cholangiopancreatography
Digestion
2024
Use of artificial intelligence for liver diseases: A survey from the EASL congress 2024
JHEP Reports
2024
In-context learning enables multimodal large language models to classify cancer pathology images
Nature Communications
2025
Counterfactual Diffusion Models for Interpretable Morphology-based Explanations of Artificial Intelligence Models in Pathology
bioRxiv
2024
Large language models as a diagnostic support tool in neuropathology
The Journal of Pathology Clinical Research
2024
Detection of suicidality from medical text using privacy-preserving large language models
The British Journal of Psychiatry
2024
Expert-Guided Large Language Models for Clinical Decision Support in Precision Oncology
JCO Precision Oncology
2024
Medical large language models are susceptible to targeted misinformation attacks
npj Digital Medicine
2024
Large language model use in clinical oncology
npj Precision Oncology
2025
Large language models for structured reporting in radiology: past, present, and future
European Radiology
2025
Role of artificial intelligence in haematolymphoid diagnostics
Histopathology
2025
Automatic structuring of radiology reports with on-premise open-source large language models
European Radiology
2024
Prediction of homologous recombination deficiency from routine histology with attention-based multiple instance learning in nine different tumor types
BMC Biology
2025
Synthetic chest X-ray images from text prompts
Nature Biomedical Engineering
2024
Deep learning segmentation model for quantification of infarct size in pigs with myocardial ischemia/reperfusion
Basic Research in Cardiology
2025
Artificial Intelligence for Contrast-Enhanced Ultrasound of the Liver: A Systematic Review
Digestion
2024
Integrating large language models in care, research, and education in multiple sclerosis management
Multiple Sclerosis
2024
Privacy-preserving large language models for structured medical information retrieval
npj Digital Medicine
2025
From whole-slide image to biomarker prediction: end-to-end weakly supervised deep learning in computational pathology
Nature Protocols
2024
LLM-AIx: An open source pipeline for Information Extraction from unstructured medical text based on privacy preserving Large Language Models
medRxiv
2024
Reconstruction of patient-specific confounders in AI-based radiologic image interpretation using generative pretraining
Cell Reports Medicine
2024
The age of foundation models
Nature Reviews Clinical Oncology
2024
Developing a low-cost, open-source, locally manufactured workstation and computational pipeline for automated histopathology evaluation using deep learning
EBioMedicine
2024
Large language models could make natural language again the universal interface of healthcare
Nature Medicine
2024
A future role for health applications of large language models depends on regulators enforcing safety standards
The Lancet Digital Health
2024
Deep sight: enhancing periprocedural adverse event recording in endoscopy by structuring text documentation with privacy-preserving large language models
iGIE
2024
Converging deep learning and human-observed tumor-adipocyte interaction as a biomarker in colorectal cancer
Communications Medicine
2024
Navigating the European Union Artificial Intelligence Act for Healthcare
npj Digital Medicine
2024
Weakly Supervised Deep Learning in Radiology
Radiology
2024
Intraindividual Comparison of Different Methods for Automated BPE Assessment at Breast MRI: A Call for Standardization
Radiology
2024
Large-scale external validation and meta-analysis of gene methylation biomarkers in tumor tissue for colorectal cancer prognosis
EBioMedicine
2024
Artificial Intelligence in Colorectal Cancer: From Patient Screening over Tailoring Treatment Decisions to Identification of Novel Biomarkers
Digestion
2024
Artificial intelligence
Cancer Cell
2024
A simple clinical score to reduce unnecessary testing for Puumala hantavirus
PLoS One
2024
Deep learning for dual detection of microsatellite instability and POLE mutations in colorectal cancer histopathology
npj Precision Oncology
2024
A guide to artificial intelligence for cancer researchers
Nature Reviews Cancer
2024
Histopathological evaluation of abdominal aortic aneurysms with deep learning
medRxiv
2024
Using histopathology latent diffusion models as privacy-preserving dataset augmenters improves downstream classification performance
Computers in Biology and Medicine
2024
Patients' and dermatologists' preferences in artificial intelligence-driven skin cancer diagnostics: A prospective multicentric survey study
Journal of the American Academy of Dermatology
2024
Augmented non-hallucinating large language models as medical information curators
npj Digital Medicine
2024
Guardrails for the use of generalist AI in cancer care
Nature Reviews Cancer
2024
Artificial intelligence in liver cancer - new tools for research and patient management
Nature Reviews Gastroenterology & Hepatology
2024
Data Extraction from Free-Text Reports on Mechanical Thrombectomy in Acute Ischemic Stroke Using ChatGPT: A Retrospective Analysis
Radiology
2024
The digital revolution in pathology: Towards a smarter approach to research and treatment
Tumori
2024
Reporting guidelines in medical artificial intelligence: a systematic review and meta-analysis
Communications Medicine
2024
From research to reality: The role of artificial intelligence applications in HCC care
Clinical Liver Disease
2024
Deep learning in cancer genomics and histopathology
Genome Medicine
2024
Large language models and multimodal foundation models for precision oncology
npj Precision Oncology
2024
3-Dimensional Reconstruction From Histopathological Sections: A Systematic Review
Laboratory Investigation
2024
A systematic pan-cancer study on deep learning-based prediction of multi-omic biomarkers from routine pathology images
Communications Medicine
2024
Author Correction: A pilot study on the efficacy of GPT-4 in providing orthopedic treatment recommendations from MRI reports
Scientific Reports
2024
Author Correction: Regression-based Deep-Learning predicts molecular biomarkers from pathology slides
Nature Communications
2024
Automated curation of large-scale cancer histopathology image datasets using deep learning
Histopathology
2024
Large language models streamline automated machine learning for clinical studies
Nature Communications
2024
Regression-based Deep-Learning predicts molecular biomarkers from pathology slides
Nature Communications
2024
Enhancing diagnostic deep learning via self-supervised pretraining on large-scale, unlabeled non-medical images
European Radiology Experimental
2024
Federated Learning for Decentralized Artificial Intelligence in Melanoma Diagnostics
JAMA Dermatology
2024
A systematic analysis of deep learning in genomics and histopathology for precision oncology
BMC Medical Genomics
2024
New regulatory thinking is needed for AI-based personalised drug and cell therapies in precision oncology
npj Precision Oncology
2024
Using multiple real-world dermoscopic photographs of one lesion improves melanoma classification via deep learning
Journal of the American Academy of Dermatology
2024
Weakly Supervised Deep Learning Predicts Immunotherapy Response in Solid Tumors Based on PD-L1 Expression
Cancer Research Communications
2024
End-to-end prognostication in colorectal cancer by deep learning: a retrospective, multicentre study
The Lancet Digital Health
2023
Direct image to subtype prediction for brain tumors using deep learning
Neuro-oncology Advances
2024
Encrypted federated learning for secure decentralized collaboration in cancer image analysis
Medical Image Analysis
2024
Extracting structured information from unstructured histopathology reports using generative pre-trained transformer 4 (GPT-4)
The Journal of Pathology
2023
Deep learning-based phenotyping reclassifies combined hepatocellular-cholangiocarcinoma
Nature Communications
2024
Novel biomarker SARIFA in colorectal cancer: highly prognostic, not genetically driven and histologic indicator of a distinct tumor biology
Cancer Gene Therapy
2023
A pilot study on the efficacy of GPT-4 in providing orthopedic treatment recommendations from MRI reports
Scientific Reports
2024
CpG-biomarkers in tumor tissue and prediction models for the survival of colorectal cancer: A systematic review and external validation study
Critical Reviews in Oncology/hematology
2023
Artificial intelligence-based pathology as a biomarker of sensitivity to atezolizumab-bevacizumab in patients with hepatocellular carcinoma: a multicentre retrospective study
The Lancet Oncology
2023
Prediction models for hormone receptor status in female breast cancer do not extend to males: further evidence of sex-based disparity in breast cancer
npj Breast Cancer
2023
Validation of MSIntuit as an AI-based pre-screening tool for MSI detection from colorectal cancer histology slides
Nature Communications
2023
Deep learning trained on lymph node status predicts outcome from gastric cancer histopathology: a retrospective multicentric study
European Journal of Cancer (Oxford, England
2023
Large language models should be used as scientific reasoning engines, not knowledge databases
Nature Medicine
2024
Large Language Models in Uro-oncology
European Urology Oncology
2023
The future landscape of large language models in medicine
Communications Medicine
2023
Multimodal Deep Learning for Integrating Chest Radiographs and Clinical Parameters: A Case for Transformers
Radiology
2023
A 3-dimensional histology computer model of malignant melanoma and its implications for digital pathology
European Journal of Cancer (Oxford, England
2023
Machine learning in the identification of prognostic DNA methylation biomarkers among patients with cancer: A systematic review of epigenome-wide studies
Artificial Intelligence in Medicine
2023
Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study
Cancer Cell
2023
Can ChatGPT explain it? Use of artificial intelligence in multiple sclerosis communication
Neurological Research and Practice
2023
Fibroglandular tissue segmentation in breast MRI using vision transformers: a multi-institutional evaluation
Scientific Reports
2024
The ecological footprint of medical AI
European Radiology
2023
Deep Learning-Enabled Diagnosis of Liver Adenocarcinoma
Gastroenterology
2023
A multimodal comparison of latent denoising diffusion probabilistic models and generative adversarial networks for medical image synthesis
Scientific Reports
2023
Medical transformer for multimodal survival prediction in intensive care: integration of imaging and non-imaging data
Scientific Reports
2023
Sublethal necroptosis signaling promotes inflammation and liver cancer
Immunity
2023
An MRI Deep Learning Model Predicts Outcome in Rectal Cancer
Radiology
2023
Deep learning-based subtyping of gastric cancer histology predicts clinical outcome: a multi-institutional retrospective study
Gastric Cancer
2023
Prediction of heart transplant rejection from routine pathology slides with self-supervised deep learning
European Heart Journal Digital Health
2023
A framework for artificial intelligence in cancer research and precision oncology
npj Precision Oncology
2023
Denoising diffusion probabilistic models for 3D medical image generation
Scientific Reports
2023
Collaborative training of medical artificial intelligence models with non-uniform labels
Scientific Reports
2023
Optical coherence tomography combined with convolutional neural networks can differentiate between intrahepatic cholangiocarcinoma and liver parenchyma ex vivo
Journal of Cancer Research and Clinical Oncology
2023
Self-supervised attention-based deep learning for pan-cancer mutation prediction from histopathology
npj Precision Oncology
2023
Generalizable biomarker prediction from cancer pathology slides with self-supervised deep learning: A retrospective multi-centric study
Cell Reports Medicine
2023
Direct prediction of Homologous Recombination Deficiency from routine histology in ten different tumor types with attention-based Multiple Instance Learning: a development and validation study
medRxiv
2023
Using Machine Learning to Reduce the Need for Contrast Agents in Breast MRI through Synthetic Images
Radiology
2023
Overcoming the challenges to implementation of artificial intelligence in pathology
Journal of the National Cancer Institute
2023
Artificial intelligence in oncology: chances and pitfalls
Journal of Cancer Research and Clinical Oncology
2023
An overview and a roadmap for artificial intelligence in hematology and oncology
Journal of Cancer Research and Clinical Oncology
2023
Characterisation of tumour-immune phenotypes and PD-L1 positivity in squamous bladder cancer
BMC Cancer
2023
An in silico model to study the impact of carbonic anhydrase IX expression on tumour growth and anti-PD-1 therapy
Journal of the Royal Society, Interface
2023
Multistain deep learning for prediction of prognosis and therapy response in colorectal cancer
Nature Medicine
2023
Artificial Intelligence for Clinical Interpretation of Bedside Chest Radiographs
Radiology
2022
Artificial intelligence for precision medicine in autoimmune liver disease
Frontiers in Immunology
2023
Validation of the prognostic value of CD3 and CD8 cell densities analogous to the Immunoscore® by stage and location of colorectal cancer: an independent patient cohort study
The Journal of Pathology Clinical Research
2023
Multimodal deep learning: An improvement in prognostication or a reflection of batch effect?
Cancer Cell
2023
Direct prediction of genetic aberrations from pathology images in gastric cancer with swarm learning
Gastric Cancer
2022
Can the Kuznetsov Model Replicate and Predict Cancer Growth in Humans?
Bulletin of Mathematical Biology
2022
Adversarial attacks and adversarial robustness in computational pathology
Nature Communications
2022
Golgi Protein 73 (GP73) Serum Levels Predict Outcome after Resection of Biliary Tract Cancer
Cancers
2022
Artificial intelligence in histopathology: enhancing cancer research and clinical oncology
Nature Cancer
2022
Erratum to 'Benchmarking weakly-supervised deep learning pipelines for whole slide classification in computational pathology' Medical Image Analysis, Volume 79, July 2022, 102474
Medical Image Analysis
2022
Second-line therapy with nivolumab plus ipilimumab for older patients with oesophageal squamous cell cancer (RAMONA): a multicentre, open-label phase 2 trial
The Lancet Healthy Longevity
2023
Facts and Hopes on the Use of Artificial Intelligence for Predictive Immunotherapy Biomarkers in Cancer
Clinical Cancer Research
2022
Nestin as a diagnostic and prognostic marker for combined hepatocellular-cholangiocarcinoma
Journal of Hepatology
2022
Deep learning can predict survival directly from histology in clear cell renal cell carcinoma
PLoS One
2022
Model soups improve performance of dermoscopic skin cancer classifiers
European Journal of Cancer (Oxford, England
2022
Uncertainty Estimation in Medical Image Classification: Systematic Review
JMIR Medical Informatics
2022
Medical domain knowledge in domain-agnostic generative AI
npj Digital Medicine
2022
Response to letter entitled: Re: Integration of deep learning-based image analysis and genomic data in cancer pathology: A systematic review
European Journal of Cancer (Oxford, England
2022
Artificial intelligence in Barrett's oesophagus and the need for shared and combined data
United European Gastroenterology Journal
2022
Benchmarking weakly-supervised deep learning pipelines for whole slide classification in computational pathology
Medical Image Analysis
2022
Clinical relevance of biomarkers in cholangiocarcinoma: critical revision and future directions
Gut
2022
Swarm learning for decentralized artificial intelligence in cancer histopathology
Nature Medicine
2022
Explainable artificial intelligence in skin cancer recognition: A systematic review
European Journal of Cancer (Oxford, England
2022
The future of artificial intelligence in digital pathology - results of a survey across stakeholder groups
Histopathology
2022
Artificial intelligence to identify genetic alterations in conventional histopathology
The Journal of Pathology
2022
Weakly supervised end-to-end artificial intelligence in gastrointestinal endoscopy
Scientific Reports
2022
Predicting Mutational Status of Driver and Suppressor Genes Directly from Histopathology With Deep Learning: A Systematic Study Across 23 Solid Tumor Types
Frontiers in Genetics
2022
Artificial intelligence in liver diseases: Improving diagnostics, prognostics and response prediction
JHEP Reports
2022
The influence of computer-aided polyp detection systems on reaction time for polyp detection and eye gaze
Endoscopy
2022
Artificial intelligence predicts immune and inflammatory gene signatures directly from hepatocellular carcinoma histology
Journal of Hepatology
2022
Classical mathematical models for prediction of response to chemotherapy and immunotherapy
PLoS Computational Biology
2022
Spatial structure governs the mode of tumour evolution
Nature Ecology & Evolution
2022
Integration of deep learning-based image analysis and genomic data in cancer pathology: A systematic review
European Journal of Cancer (Oxford, England
2022
Deep learning-based classification of kidney transplant pathology: a retrospective, multicentre, proof-of-concept study
The Lancet Digital Health
2022
Deep learning identifies inflamed fat as a risk factor for lymph node metastasis in early colorectal cancer
The Journal of Pathology
2021
Deep learning can predict lymph node status directly from histology in colorectal cancer
European Journal of Cancer (Oxford, England
2022
Weakly supervised annotation-free cancer detection and prediction of genotype in routine histopathology
The Journal of Pathology
2021
Skin cancer classification via convolutional neural networks: systematic review of studies involving human experts
European Journal of Cancer (Oxford, England
2021
Development and validation of deep learning classifiers to detect Epstein-Barr virus and microsatellite instability status in gastric cancer: a retrospective multicentre cohort study
The Lancet Digital Health
2021
Gastrointestinal cancer classification and prognostication from histology using deep learning: Systematic review
European Journal of Cancer (Oxford, England
2021
A benchmark for neural network robustness in skin cancer classification
European Journal of Cancer (Oxford, England
2021
The Presence of Small Nerve Fibers in the Tumor Microenvironment as Predictive Biomarker of Oncological Outcome Following Partial Hepatectomy for Intrahepatic Cholangiocarcinoma
Cancers
2021
Deep learning approach to predict sentinel lymph node status directly from routine histology of primary melanoma tumours
European Journal of Cancer (Oxford, England
2021
The impact of site-specific digital histology signatures on deep learning model accuracy and bias
Nature Communications
2021
Integrating Patient Data Into Skin Cancer Classification Using Convolutional Neural Networks: Systematic Review
Journal of Medical Internet Research
2021
Nerve Fibers in the Tumor Microenvironment as a Novel Biomarker for Oncological Outcome in Patients Undergoing Surgery for Perihilar Cholangiocarcinoma
Liver Cancer
2021
Artificial Intelligence Can Cut Costs While Maintaining Accuracy in Colorectal Cancer Genotyping
Frontiers in Oncology
2021
Deep Transfer Learning Approach for Automatic Recognition of Drug Toxicity and Inhibition of SARS-CoV-2
Viruses
2022
Artificial Intelligence-based Detection of FGFR3 Mutational Status Directly from Routine Histology in Bladder Cancer: A Possible Preselection for Molecular Testing?
European Urology Focus
2021
Serum levels of soluble B and T lymphocyte attenuator predict overall survival in patients undergoing immune checkpoint inhibitor therapy for solid malignancies
International Journal of Cancer
2021
Serum Levels of Soluble Urokinase Plasminogen Activator Receptor Predict Tumor Response and Outcome to Immune Checkpoint Inhibitor Therapy
Frontiers in Oncology
2021
Combining CNN-based histologic whole slide image analysis and patient data to improve skin cancer classification
European Journal of Cancer (Oxford, England
2020
Pan-cancer image-based detection of clinically actionable genetic alterations
Nature Cancer
2021
Next Generation Imaging Techniques to Define Immune Topographies in Solid Tumors
Frontiers in Immunology
2022
Diagnostic performance of artificial intelligence for histologic melanoma recognition compared to 18 international expert pathologists
Journal of the American Academy of Dermatology
2021
Nerve Fibers in the Tumor Microenvironment Are Co-Localized with Lymphoid Aggregates in Pancreatic Cancer
Journal of Clinical Medicine
2021
Deep learning detects genetic alterations in cancer histology generated by adversarial networks
The Journal of Pathology
2021
Hidden Variables in Deep Learning Digital Pathology and Their Potential to Cause Batch Effects: Prediction Model Study
Journal of Medical Internet Research
2021
Robustness of convolutional neural networks in recognition of pigmented skin lesions
European Journal of Cancer (Oxford, England
2021
Nerve fibers in the tumor microenvironment in neurotropic cancer-pancreatic cancer and cholangiocarcinoma
Oncogene
2021
Artificial intelligence-based pathology for gastrointestinal and hepatobiliary cancers
Gut
2021
Deep learning in cancer pathology: a new generation of clinical biomarkers
British Journal of Cancer
2020
Completion rate and impact on physician-patient relationship of video consultations in medical oncology: a randomised controlled open-label trial
ESMO Open
2020
Experimental Assessment of Color Deconvolution and Color Normalization for Automated Classification of Histology Images Stained with Hematoxylin and Eosin
Cancers
2020
Author Correction: Pan-cancer image-based detection of clinically actionable genetic alterations
Nature Cancer
2020
Artificial intelligence in gastroenterology]
Deutsche Medizinische Wochenschrift
2021
Response to neoadjuvant treatment among rectal cancer patients in a population-based cohort
International Journal of Colorectal Disease
2020
Different scaling of linear models and deep learning in UKBiobank brain images versus machine-learning datasets
Nature Communications
2020
Skeletal Muscle Composition Predicts Outcome in Critically Ill Patients
Critical Care Explorations
2020
Development of AI-based pathology biomarkers in gastrointestinal and liver cancer
Nature Reviews Gastroenterology & Hepatology
2020
Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning
Gastroenterology
2020
Effects of Label Noise on Deep Learning-Based Skin Cancer Classification
Frontiers in Medicine
2020
Circulating levels of soluble urokinase plasminogen activator receptor predict outcome after resection of biliary tract cancer
JHEP Reports
2019
CCR5 status and metastatic progression in colorectal cancer
Oncoimmunology
2019
Aryl hydrocarbon receptor nuclear translocator-like (ARNTL/BMAL1) is associated with bevacizumab resistance in colorectal cancer via regulation of vascular endothelial growth factor A
EBioMedicine
2019
CD163+ immune cell infiltrates and presence of CD54+ microvessels are prognostic markers for patients with embryonal rhabdomyosarcoma
Scientific Reports
2019
Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer
Nature Medicine
2019
Harnessing the innate immune system and local immunological microenvironment to treat colorectal cancer
British Journal of Cancer
2019
High baseline soluble urokinase plasminogen activator receptor (suPAR) serum levels indicate adverse outcome after resection of pancreatic adenocarcinoma
Carcinogenesis
2019
Predicting survival from colorectal cancer histology slides using deep learning: A retrospective multicenter study
PLoS Medicine
2019
Serum levels of miR-29, miR-122, miR-155 and miR-192 are elevated in patients with cholangiocarcinoma
PLoS One
2019
Nuclear Translocation of RELB Is Increased in Diseased Human Liver and Promotes Ductular Reaction and Biliary Fibrosis in Mice
Gastroenterology
2018
Topography of cancer-associated immune cells in human solid tumors
eLife
2018
Automatic evaluation of tumor budding in immunohistochemically stained colorectal carcinomas and correlation to clinical outcome
Diagnostic Pathology
2018
High-Throughput Screening of Combinatorial Immunotherapies with Patient-Specific In Silico Models of Metastatic Colorectal Cancer
Cancer Research
2018
Large-scale database mining reveals hidden trends and future directions for cancer immunotherapy
Oncoimmunology
2018
Genomics and emerging biomarkers for immunotherapy of colorectal cancer
Seminars in Cancer Biology
2017
In Silico Modeling of Immunotherapy and Stroma-Targeting Therapies in Human Colorectal Cancer
Cancer Research
2017
Polyphonic sonification of electrocardiography signals for diagnosis of cardiac pathologies
Scientific Reports
2017
Identification of a characteristic vascular belt zone in human colorectal cancer
PLoS One
2017
Color-coded visualization of magnetic resonance imaging multiparametric maps
Scientific Reports
2016
Multi-class texture analysis in colorectal cancer histology
Scientific Reports
2015
New Colors for Histology: Optimized Bivariate Color Maps Increase Perceptual Contrast in Histological Images
PLoS One
2015
Continuous representation of tumor microvessel density and detection of angiogenic hotspots in histological whole-slide images
Oncotarget
2014
Transgenic mouse models of corneal neovascularization: new perspectives for angiogenesis research
Investigative Ophthalmology & Visual Science
2014
Angiopoietin-1 is regulated by miR-204 and contributes to corneal neovascularization in KLEIP-deficient mice
Investigative Ophthalmology & Visual Science
2013
Rho guanine exchange factors in blood vessels: fine-tuners of angiogenesis and vascular function
Experimental Cell Research
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